View abstract. 2019;29(5):526-531. Lis DM, Baar K. Effects of Different Vitamin C-Enriched Collagen Derivatives on Collagen Synthesis. ; Vitamin C reverses sun damage, boosts collagen synthesis… Peptides function as activators to stimulate the synthesis of major constituents of the skin such as collagen. Transcription (in … It is used extensively in the extracellular matrix, which forms the basis for most connective tissue. How Can You Increase Collagen Synthesis? Supplemental intake of the following can boost collagen production: Retinol is a derivative of vitamin A which boosts collagen synthesis and speeds up cell turnover for youthful looking skin. In the dermis, peptides are able to enter the skin cell and interact with specific proteins to signal the upregulation of collagen synthesis. Collagen is a primary component in the connective tissues, such as tendons and ligaments. Collagen synthesis refers to the process of collagen … Int J Sport Nutr Exerc Metab. Collagen synthesis is a multi-step procedure requiring the use of many different structures both within and outside of fibroblasts (special collagen-producing cells within connective tissue). Supplements.